Sexual Health Is a Medical Issue: The Physiology, the Research, and How We Treat It
- Dr. Frank J. Welch, MD, M.S.P.H., FACPM, ABAARM
- Apr 3
- 2 min read
Updated: Apr 13

Sexual health is not a peripheral concern—it is a central dimension of physical and emotional wellbeing. The World Health Organization defines sexual health as a state of physical, emotional, mental, and social wellbeing in relation to sexuality. Research consistently demonstrates that sexual dysfunction is associated with reduced quality of life, relationship distress, and in many cases, is a marker of underlying physiologic conditions that warrant clinical attention.
The Physiology of Sexual Function
Sexual function in both men and women is governed by a complex interaction of hormonal, vascular, neurological, and psychological factors. In men, erectile function depends on adequate testosterone levels, nitric oxide-mediated vasodilation, intact parasympathetic nerve signaling, and healthy endothelial function. Erectile dysfunction is now recognized as a potential early marker of cardiovascular disease, as the penile vasculature is smaller and more sensitive to endothelial dysfunction than coronary vessels. In women, libido, arousal, and tissue health are driven by estrogen, testosterone, and progesterone—all of which decline through perimenopause and menopause—along with neurologic and vascular factors.
Common Sexual Health Concerns We Address
At Oak Health Institute, we address a range of sexual health concerns in both men and women including erectile dysfunction, reduced libido in men and women, arousal difficulty and reduced sensation in women, vaginal dryness and dyspareunia associated with hormone decline, and performance anxiety with neurologic components. Each of these has identifiable physiologic drivers that respond to evidence-based intervention.
Evidence-Based Treatments
Our sexual health protocols draw on multiple evidence-based modalities. Testosterone optimization restores hormonal drivers of libido and sexual function in both men and women; research published in the Journal of Sexual Medicine demonstrates significant improvements in sexual desire, arousal, and satisfaction with testosterone therapy in appropriately selected patients. PT-141 (bremelanotide) is an FDA-approved melanocortin receptor agonist that works centrally to enhance sexual desire—distinct from PDE5 inhibitors, which work peripherally on vascular smooth muscle. For women, low-dose topical estrogen and testosterone can address tissue-level changes associated with genitourinary syndrome of menopause. PDE5 inhibitors remain highly effective for erectile dysfunction and are sometimes used in novel ways for women's arousal as well.
Discretion and Clinical Expertise
Sexual health concerns are among the most underreported in clinical medicine. Patients frequently hesitate to raise them with their primary care providers, and many providers lack the specialized training to address them comprehensively. At Oak Health Institute, sexual health is treated as a clinical pillar—evaluated, discussed, and addressed with the same evidence-based rigor we bring to hormone optimization and metabolic health. All care is delivered with complete discretion via telemedicine, allowing patients to have these conversations from the privacy of their own environment.
If sexual health concerns are affecting your quality of life, we invite you to schedule a confidential consultation with our medical team. You deserve comprehensive care—and that includes this.



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