DIM Complex is a clinical-grade formula designed to support healthy hormone metabolism in both women and men. Featuring 150 mg of DIM, broccoli extract (20:1), calcium D-glucarate, and BioPerine® for enhanced absorption, this formula promotes balanced estrogen activity, efficient detoxification, and improved metabolic wellness.
DIM (Diindolylmethane) helps shift estrogen toward beneficial metabolites, supporting clear skin, mood stability, and hormonal balance during perimenopause, menopause, and testosterone therapy. Broccoli-derived compounds enhance phase II liver detoxification, while calcium D-glucarate assists with the natural elimination of hormone byproducts. BioPerine® ensures optimal uptake and clinical effectiveness.
Ideal for anti-aging clinics, hormone therapy practices, and wellness providers, DIM Complex offers comprehensive support for patients seeking a more balanced hormonal environment.
DIM Complex
DIM is derived from cruciferous vegetables and is among the most studied natural compounds for supporting estrogen detoxification. Clinical Benefits: • Increases beneficial 2-hydroxy estrogen metabolites [1,3,5] • Improves 2-OH : 16-OH balance [5,6] • Supports SHBG levels [1] • Reduces aromatization in men on TRT [2] • Helps balance estrogen–testosterone pathways during HRT / TRT • Shown in human trials to shift estrogen metabolism towards beneficial pathways [1,3]
Scientific References 1. Thomson CA et al. Breast Cancer Res Treat. 2017. 2. Chen I et al. Biochem Pharmacol. 1998. 3. Sámano R et al. Nutr Cancer. 2022. 4. Newman M, Smeaton J. BMC Complement Med. 2024. 5. Michnovicz JJ, Bradlow HL. J Nutr. 1994. 6. Zeligs MA et al. Carcinogenesis. 2020. 7. Fahey JW et al. Appl Sci. 2025. 8. Clarke J et al. Toxicol Appl Pharmacol. 2008. 9. Higdon J et al. Phytochem Rev. 2007. 10. Shapiro TA et al. Cancer Epidemiol Biomarkers Prev. 2001. 11. Kensler TW et al. Proc Natl Acad Sci. 2005. 12. Walaszek Z. J Nutr. 1997. 13. Kim DH et al. J Pharm Sci. 1994. 14. Walaszek Z et al. Cancer Lett. 1986. 15. Shoba G et al. Planta Med. 1998. 16. Atal CK, Dubey RK. Indian J Pharmacol. 1985. 17. Bajad S et al. Drug Metab Dispos. 2003.